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1

Nordihydroguaiaretic acid (NDGA), an inhibitor of the HER2 and IGF-1 receptor tyrosine kinases, blocks the growth of HER2-overexpressing human breast cancer cells

Marianna Zavodovskaya, Michael J. Campbell, Betty A. Maddux, Laura Shiry, Geoffrey Allan, Leslie Hodges, Peter Kushner, John A. Kerner, Jack F. Youngren, Ira D. Goldfine

Journal:

Journal of Cellular Biochemistry

Year:

2008

Language:

english

File:

PDF, 268 KB

english, 2008

2

Cerebral Salt Wasting Syndrome: Diagnosis By Urine Sodium Excretion

Arieff, Allen I., Gabbai, Ramin, Goldfine, Ira D.

Journal:

The American Journal of the Medical Sciences

Year:

2017

Language:

english

File:

PDF, 674 KB

english, 2017

3

Nordihydroguaiaretic Acid (NDGA) Inhibits the IGF-1 and c-erbB2/HER2/neu Receptors and Suppresses Growth in Breast Cancer Cells

Jack F. Youngren, Karissa Gable, Cristina Penaranda, Betty A. Maddux, Marianna Zavodovskaya, Margaret Lobo, Michael Campbell, John Kerner, Ira D. Goldfine

Journal:

Breast Cancer Research and Treatment

Year:

2005

Language:

english

File:

PDF, 330 KB

english, 2005

4

The endocrine secretion of human insulin and growth hormone by exocrine glands of the gastrointestinal tract

Goldfine, Ira D., German, Michael S., Tseng, Hsien-Chen, Wang, Juemin, Bolaffi, Janice L., Chen, Je-Wei, Olson, David C., Rothman, Stephen S.

Journal:

Nature Biotechnology

Year:

1997

File:

PDF, 710 KB

1997

5

In vitro and in vivo prevention of HIV protease inhibitor-induced insulin resistance by a novel small molecule insulin receptor activator

Mingshan Cheng, Seiyu Chen, Steven R. Schow, Vara Prasad Manchem, Wayne R. Spevak, Cristina P. Cristobal, Songyuan Shi, Robert W. Macsata, Robert T. Lum, Ira D. Goldfine, James G. Keck

Journal:

Journal of Cellular Biochemistry

Year:

2004

Language:

english

File:

PDF, 264 KB

english, 2004

6

Cloning and Characterization of the Human Insulin-Like Growth Factor-I Receptor Gene 5′-Flanking Region

MAMULA, PAUL W., GOLDFINE, IRA D.

Journal:

DNA and Cell Biology

Year:

1992

Language:

english

File:

PDF, 2.83 MB

english, 1992

7

Insulin autoimmune syndrome (Hirata Disease) in European Caucasians taking α-lipoic acid

Gullo, Damiano, Evans, Joseph L., Sortino, Grazia, Goldfine, Ira D., Vigneri, Riccardo

Journal:

Clinical Endocrinology

Year:

2014

Language:

english

File:

PDF, 105 KB

english, 2014

8

Gender Differences in the Relationship of ENPP1/PC-1 Variants to Obesity in a Turkish Population

Sinan Tanyolaç, Robert W. Mahley, Uğur Hodoglugil, Ira D. Goldfine

Journal:

Year:

2008

Language:

english

File:

PDF, 178 KB

english, 2008

9

Decreased binding of insulin to its receptors in rats with hormone induced insulin resistance

Ira D. Goldfine, C.Ronald Kahn, David M. Neville Jr., Jesse Roth, Mary M. Garrison, Robert W. Bates

Journal:

Biochemical and Biophysical Research Communications

Year:

1973

Language:

english

File:

PDF, 348 KB

english, 1973

10

Insulin receptors and the site of action of insulin

Ira D. Goldfine

Journal:

Year:

1978

Language:

english

File:

PDF, 663 KB

english, 1978

11

Acromegaly with normal growth-hormone levels and pituitary histology

Feingold, Kenneth R., Goldfine, Ira D., Weinstein, Philip R.

Journal:

Journal of Neurosurgery

Year:

1979

Language:

english

File:

PDF, 1.19 MB

english, 1979

12

Differential Effects of Fibroblast Growth Factor on Insulin Receptor and Muscle Specific Protein Gene Expression in BC3H-1 Myocytes

Brunetti, Antonio, Goldfine, Ira D.

Journal:

Molecular Endocrinology

Year:

1990

Language:

english

File:

PDF, 750 KB

english, 1990

13

Insulin-stimulated cell growth in insulin receptor substrate-1–deficient ZR-75-1 cells is mediated by a phosphatidylinositol-3-kinase–independent pathway

Biancamaria Gliozzo, Chin K. Sung, PierLuigi Scalia, Vincenzo Papa, Francesco Frasca, Laura Sciacca, Francesco Giorgino, Giovanni Milazzo, Ira D. Goldfine, Riccardo Vigneri, Vincenzo Pezzino

Journal:

Journal of Cellular Biochemistry

Year:

1998

Language:

english

File:

PDF, 149 KB

english, 1998

14

Chromium picolinate and biotin combination improves glucose metabolism in treated, uncontrolled overweight to obese patients with type 2 diabetes

Cesar A. Albarracin, Burcham C. Fuqua, Joseph L. Evans, Ira D. Goldfine

Journal:

Diabetes/Metabolism Research and Reviews

Year:

2008

Language:

english

File:

PDF, 186 KB

english, 2008

15

Parallel Synthesis of Diarylureas and Their Evaluation as Inhibitors of Insulin-Like Growth Factor Receptor

Anderson, Marc O., Yu, Hong, Penaranda, Cristina, Maddux, Betty A., Goldfine, Ira D., Youngren, Jack F., Guy, R. Kiplin

Journal:

Journal of Combinatorial Chemistry

Year:

2006

Language:

english

File:

PDF, 134 KB

english, 2006

16

Proglumide (gastrin and cholecystokinin receptor antagonist) inhibits insulin secretion in vitro

Eugen J. Verspohl, Gabriele Wunderle, Hermann P. T. Ammon, John A. Williams, Ira D. Goldfine

Journal:

Naunyn-Schmiedeberg's Archives of Pharmacology

Year:

1986

Language:

english

File:

PDF, 446 KB

english, 1986

17

Glucocorticoids Increase Amylase mRNA Levels, Secretory Organelles, and Secretion in Pancreatic Acinar AR42J Cells

Craig D. Logsdon, Joachim Moessner, John A. Williams and Ira D. Goldfine

Journal:

The Journal of Cell Biology

Year:

1985

Language:

english

File:

PDF, 3.31 MB

english, 1985

18

Physiological Concentrations of Cholecystokinin Stimulate Amino Acid-Induced Insulin Release in Humans*

RUSHAKOFF, ROBERT J., GOLDFINE, IRA D., CARTER, JACQUELINE D., LIDDLE, RODGER A.

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

1987

Language:

english

File:

PDF, 959 KB

english, 1987

19

Inhibitory effects of nordihydroguaiaretic acid (NDGA) on the IGF-1 receptor and androgen dependent growth of LAPC-4 prostate cancer cells

Charles J. Ryan, Marianna Zavodovskaya, Jack F. Youngren, Michael Campbell, Marc Diamond, Jeremy Jones, Laura Shiry, Geoffrey Allan, Betty A. Maddux, Ira D. Goldfine

Journal:

Year:

2008

Language:

english

File:

PDF, 275 KB

english, 2008

20

Insulin receptor activation by IGF-II in breast cancers: evidence for a new autocrine/paracrine mechanism

Sciacca, Laura, Costantino, Angela, Pandini, Giuseppe, Mineo, Rossana, Frasca, Francesco, Scalia, Pierluigi, Sbraccia, Paolo, Goldfine, Ira D, Vigneri, Riccardo, Belfiore, Antonino

Journal:

Year:

1999

Language:

english

File:

PDF, 186 KB

english, 1999

21

Rodent Insulin Receptors Are Immunologically Different from Other Mammalian Insulin Receptors

Zhi.-Qiang Tong, Elaine Jack, Margaret Moule, Ira D. Goldfine, Cecil C. Yip

Journal:

General and Comparative Endocrinology

Year:

1994

File:

PDF, 370 KB

1994

22

Binding of Insulin to Isolated Nuclei

Ira D. Goldfine and George J. Smith

Journal:

Proceedings of the National Academy of Sciences

Year:

1976

Language:

english

File:

PDF, 1.16 MB

english, 1976

23

Identification and characterization of the ligand-binding domain of insulin receptor by use of an anti-peptide antiserum against amino acid sequence 241-251 of the .alpha. subunit

Yip, Cecil C., Grunfeld, Carl, Goldfine, Ira D.

Journal:

Year:

1991

Language:

english

File:

PDF, 2.44 MB

english, 1991

24

P-62: Role of phosphatidylinositol-3-kinase and S6 kinase in insulin-stimulated glycogen synthesis

Sánchez-Margalet, Victor, Goldfine, Ira D., Sung, Chin K.

Journal:

Experimental and Clinical Endocrinology & Diabetes

Year:

1996

Language:

english

File:

PDF, 12 KB

english, 1996

25

Stimulation of the Uptake of α-Aminoisobutyric Acid in Rat Thymocytes by L-Triiodothyronine: A Comparison with Insulin and Dibutyryl Cyclic AMP

GOLDFINE, IRA D., SIMONS, CYRENA G., INGBAR, SIDNEY H.

Journal:

Year:

1975

Language:

english

File:

PDF, 378 KB

english, 1975

26

Inhibition of Cyclic 3′,5′-AMP Phosphodiesterase in Islet Cells and Other Tissues by Tolbutamide

GOLDFINE, IRA D., PERLMAN, ROBERT, ROTH, JESSE

Journal:

Year:

1971

File:

PDF, 426 KB

1971

27

Hypopituitarism in Acromegaly

Goldfine, Ira D.

Journal:

Archives of Internal Medicine

Year:

1972

Language:

english

File:

PDF, 469 KB

english, 1972

28

Species Specificity of Insulin Binding and Insulin Receptor Protein Tyrosine Kinase Activity*

CORDERA, RENZO, ANDRAGHETTI, GABRIELLA, GHERZI, ROBERTO, ADEZATI, LUCIANO, MONTEMURRO, ANTONIO, LAURO, RENATO, GOLDFINE, IRA D., DE PIRRO, ROBERTO

Journal:

Year:

1987

Language:

english

File:

PDF, 478 KB

english, 1987

29

ATTENUATION OF INSULIN ACTION BY AN ALLOSTERIC INSULIN RECEPTOR ANTIBODY IN HEALTHY VOLUNTEERS

Johnson, Kirk W., Neale, Ann, Gordon, Allan, Roessig, Julie, Bezwada, Padma, Vukelich, Sabine, Goldfine, Ira, Rubin, Paul

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

2017

Language:

english

File:

PDF, 1.23 MB

english, 2017

30

A monoclonal antibody to the T-cell receptor increases IGF-I receptor content in normal T-lymphocytes: Comparison with phytohemagglutinin

Klaus K. P. Hartmann, Vincenzo Papa, Eric J. Brown, Ira D. Goldfine, Stephen M. Rosenthal, Thomas G. Baier, Michael Kronenwett

Journal:

Journal of Cellular Biochemistry

Year:

1992

Language:

english

File:

PDF, 467 KB

english, 1992

31

The Molecular Basis for Oxidative Stress-Induced Insulin Resistance

Evans, Joseph L., Maddux, Betty A., Goldfine, Ira D.

Journal:

Antioxidants & Redox Signaling

Year:

2005

Language:

english

File:

PDF, 327 KB

english, 2005

32

Comparison of solubilized and purified plasma membrane and nuclear insulin receptors

Wong, Kwok Y., Hawley, Dennis, Vigneri, Riccardo, Goldfine, Ira D.

Journal:

Year:

1988

Language:

english

File:

PDF, 1.15 MB

english, 1988

33

The Insulin Receptor: Molecular Biology and Transmembrane Signaling*

GOLDFINE, IRA D.

Journal:

Endocrine Reviews

Year:

1987

Language:

english

File:

PDF, 4.82 MB

english, 1987

34

Human Autoantibodies Directed against the Human, but Not the Rat, Insulin Receptor*

PIRRO, ROBERTO DE, ROSSETTI, LUCIANO, MONTEMURRO, ANTONIO, LAURO, RENATO, GAMMELTOFT, STEEN, MADDUX, BETTY A., GOLDFINE, IRA D.

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

1985

Language:

english

File:

PDF, 502 KB

english, 1985

35

Intracellular binding sites for insulin are immunologically distinct from those on the plasma membrane

GOLDFINE, IRA D., VIGNERI, RICCARDO, COHEN, DAVID, PLIAM, NATHAN B., KAHN, C. RONALD

Journal:

Year:

1977

File:

PDF, 387 KB

1977

36

Elevated plasma cell membrane glycoprotein levels and diminished insulin receptor autophosphorylation in obese, insulin-resistant rhesus monkeys

Celia Pender, Heidi K. Ortmeyer, Barbara C. Hansen, Ira D. Goldfine, Jack F. Youngren

Journal:

Year:

2002

Language:

english

File:

PDF, 97 KB

english, 2002

37

Chromium supplementation in non-obese non-diabetic subjects is associated with a decline in insulin sensitivity

Umesh Masharani, Christine Gjerde, Shelley McCoy, Betty A Maddux, Danielle Hessler, Ira D Goldfine, Jack F Youngren

Journal:

BMC Endocrine Disorders

Year:

2012

Language:

english

File:

PDF, 258 KB

english, 2012

38

Alterations in Insulin Binding Induced by Changes in Vivo in the Levels of Glucocorticoids and Growth Hormone*

RONALD KAHN, C., GOLDFINE, IRA D., NEVILLE, DAVID M., DE MEYTS, PIERRE

Journal:

Year:

1978

Language:

english

File:

PDF, 1.28 MB

english, 1978

39

Rapid Inhibition of Basal and Glucose-Stimulated Insulin Release by Xylazine*

GOLDFINE, IRA D., ARIEFF, ALLEN I.

Journal:

Year:

1979

Language:

english

File:

PDF, 269 KB

english, 1979

40

The Role of Membrane Glycoprotein Plasma Cell Antigen 1/Ectonucleotide Pyrophosphatase Phosphodiesterase 1 in the Pathogenesis of Insulin Resistance and Related Abnormalities

Goldfine, Ira D., Maddux, Betty A., Youngren, Jack F., Reaven, Gerald, Accili, Domenico, Trischitta, Vincenzo, Vigneri, Riccardo, Frittitta, Lucia

Journal:

Endocrine Reviews

Year:

2008

Language:

english

File:

PDF, 867 KB

english, 2008

41

Methylamine and Monensin Do Not Block Insulin Internalization but Do Influence the Intracellular Distribution and Action of Insulin in Pancreatic Acini from Diabetic Mice*

POTAU, NEUS, BAILEY, ANNE C., ROACH, EILEEN, WILLIAMS, JOHN A., GOLDFINE, IRA D.

Journal:

Year:

1984

Language:

english

File:

PDF, 2.16 MB

english, 1984

42

ALTERATIONS OF BRAIN CEREBRAL CORTEX CCK RECEPTORS IN THE OB/OB MOUSE 1

SAITO, ATSUSHI, WILLIAMS, JOHN A., GOLDFINE, IRA D.

Journal:

Year:

1981

Language:

english

File:

PDF, 357 KB

english, 1981

43

A New Road for Treating the Vascular Complications of Diabetes: So Let's Step on the Gas

Evans, Joseph L., Goldfine, Ira D.

Journal:

Year:

2016

Language:

english

File:

PDF, 775 KB

english, 2016

44

Contributions of the American Journal of Physiology to the discovery of insulin

Goldfine, Ira D., Youngren, Jack F.

Journal:

American Journal of Physiology-Endocrinology and Metabolism

Year:

1998

Language:

english

File:

PDF, 32 KB

english, 1998

45

Interaction of insulin, polypeptide hormones, and growth factors with intracellular membranes

Ira D. Goldfine

Journal:

Biochimica et Biophysica Acta (BBA) - Reviews on Biomembranes

Year:

1981

Language:

english

File:

PDF, 1.38 MB

english, 1981

46

Decreased Insulin Receptor (IR) Autophosphorylation in Fibroblasts from Patients with PCOS: Effects of Serine Kinase Inhibitors and IR Activators

Li, Ming, Youngren, Jack F., Dunaif, Andrea, Goldfine, Ira D., Maddux, Betty A., Zhang, Bei B., Evans, Joseph L.

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

2002

Language:

english

File:

PDF, 227 KB

english, 2002

47

Evidence That an HMGA1 Gene Variant Associates with Type 2 Diabetes, Body Mass Index, and High-Density Lipoprotein Cholesterol in a Hispanic-American Population

Pullinger, Clive R., Goldfine, Ira D., Tanyolaç, Sinan, Movsesyan, Irina, Faynboym, Mark, Durlach, Vincent, Chiefari, Eusebio, Foti, Daniela P., Frost, Philip H., Malloy, Mary J., Brunetti, Antonio, K

Journal:

Metabolic Syndrome and Related Disorders

Year:

2014

Language:

english

File:

PDF, 145 KB

english, 2014

48

Role of gut microbiota and oxidative stress in the progression of non-alcoholic fatty liver disease to hepatocarcinoma: Current and innovative therapeutic approaches

Borrelli, Antonella, Bonelli, Patrizia, Tuccillo, Franca Maria, Goldfine, Ira D., Evans, Joseph L., Buonaguro, Franco Maria, Mancini, Aldo

Journal:

Year:

2018

Language:

english

File:

PDF, 923 KB

english, 2018

49

ASPB10 insulin induction of increased mitogenic responses and phenotypic changes in human breast epithelial cells: Evidence for enhanced interactions with the insulin-like growth factor-I receptor

Giovanni Milazzo, Laura Sciacca, Vincenzo Papa, Ira D. Goldfine, Riccardo Vigneri

Journal:

Molecular Carcinogenesis

Year:

1997

Language:

english

File:

PDF, 128 KB

english, 1997

50

Brain CCK receptors are structurally distinct from pancreas CCK receptors

Choitsu Sakamoto, John A. Williams, Ira D. Goldfine

Journal:

Biochemical and Biophysical Research Communications

Year:

1984

Language:

english

File:

PDF, 1.02 MB

english, 1984

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